Analysis of Rate‐limiting Reactions in Cephalosporin Biosynthesisa
- 1 October 1992
- journal article
- Published by Wiley in Annals of the New York Academy of Sciences
- Vol. 665 (1) , 16-26
- https://doi.org/10.1111/j.1749-6632.1992.tb42570.x
Abstract
No abstract availableKeywords
This publication has 15 references indexed in Scilit:
- The beta-lactam biosynthesis genes for isopenicillin N epimerase and deacetoxycephalosporin C synthetase are expressed from a single transcript in Streptomyces clavuligerusJournal of Bacteriology, 1990
- Use of Recombinant DNA to Improve Production of Cephalosporin C By Cephalosporium acremoniumNature Biotechnology, 1989
- Cloning, characterization, and expression in Escherichia coli of the Streptomyces clavuligerus gene encoding deacetoxycephalosporin C synthetaseJournal of Bacteriology, 1989
- Cloning and nucleotide sequence determination of the isopenicillin N synthetase gene from Streptomyces clavuligerusGene, 1988
- Production of the penicillin precursor δ-(L-α-aminoadipyl)-L-cysteinyl-D-valine (ACV) by cell-free extracts fromStreptomyces clavuligerusFEMS Microbiology Letters, 1988
- Cloning and Expression of the Fungal Expandase/hydroxylase Gene Involved in Cephalosporin BiosynthesisNature Biotechnology, 1987
- Copurification and characterization of deacetoxycephalosporin C synthetase/hydroxylase from Cephalosporium acremoniumJournal of Bacteriology, 1987
- δ -(L-α-Aminoadipyl)-L-cysteinyl-D-valine synthetase (ACV synthetase): a multifunctional enzyme with broad substrate specificity for the synthesis of penicillin and cephalosporin precursorsJournal of the American Chemical Society, 1987
- Isolation, sequence determination and expression in Escherichia coli of the isopenicillin N synthetase gene from Cephalosporium acremoniumNature, 1985
- Purification of isopenicillin N synthetaseBiochemical Journal, 1984