Acceleration of the Fluorination of Benzyl Halide by the Combination of Lead Fluoride and Sodium Salt

1 July 1992

journal article
research article
Published by Oxford University Press (OUP) in Chemistry Letters

Vol. 21 (7) , 1161-1164
https://doi.org/10.1246/cl.1992.1161

Abstract

A new composite reagent, a combination of lead fluoride (PbF₂) and a small amount of sodium salt (NaX, X = F, Br etc.) was found to be useful for facilitating heterogeneous fluorination of substituted benzyl halides in acetonitrile.

Keywords

FLUORINATION
BENZYL HALIDE
LEAD FLUORIDE
SODIUM SALT
ACCELERATION

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Metal Fluorides as Fluorinating Agents
Journal of the American Chemical Society, 1949