Translation of Varicella-Zoster Virus Genes During Human Ganglionic Latency
- 1 December 2004
- journal article
- Published by Springer Nature in Virus Genes
- Vol. 29 (3) , 317-319
- https://doi.org/10.1007/s11262-004-7434-z
Abstract
Immunohistochemical analysis of fixed tissue sections of human trigeminal ganglia (TG) and dorsal root ganglia (DRG) revealed the neuronal expression of proteins encoded by Varicella-zoster virus (VZV) genes 21, 29, 62 and 63. These proteins were detected mainly in the neuronal cytoplasm, are likely to be present in low abundance during VZV latency, and mirror the profile of VZV gene transcription.Keywords
This publication has 18 references indexed in Scilit:
- Varicella-Zoster Virus Gene 66 Transcription and Translation in Latently Infected Human GangliaJournal of Virology, 2003
- Varicella‐zoster virus latency in human gangliaReviews in Medical Virology, 2002
- Varicella-Zoster Virus Gene Expression in Latently Infected Rat Dorsal Root GangliaVirology, 2001
- Analysis of Individual Human Trigeminal Ganglia for Latent Herpes Simplex Virus Type 1 and Varicella-Zoster Virus Nucleic Acids Using Real-Time PCRJournal of Virology, 2000
- Varicella-Zoster Virus Gene Expression in Latently Infected and Explanted Human GangliaJournal of Virology, 2000
- Neurologic Complications of the Reactivation of Varicella–Zoster VirusNew England Journal of Medicine, 2000
- Aberrant intracellular localization of Varicella-Zoster virus regulatory proteins during latencyProceedings of the National Academy of Sciences, 1998
- Expression of protein encoded by varicella-zoster virus open reading frame 63 in latently infected human ganglionic neurons.Proceedings of the National Academy of Sciences, 1996
- Immunization with the immediate-early tegument protein (open reading frame 62) of varicella-zoster virus protects guinea pigs against virus challengeJournal of Virology, 1993
- Patterns of gene expression and sites of latency in human nerve ganglia are different for varicella-zoster and herpes simplex viruses.Proceedings of the National Academy of Sciences, 1988