DUODENOGASTRIC BILE REFLUX AS MEASURED BY AN ISOTOPE TECHNIQUE AND ITS CORRELATION WITH ENDOSCOPIC FINDINGS

  • 1 January 1983
    • journal article
    • research article
    • Vol. 15  (4) , 146-150
Abstract
Seventy-six patients were examined for duodenogastric reflux by gastroscopy and by a noninvasive isotope method using 99mTc-diethyliminodiacetic acid. The bile acid concentration of endoscopically aspirated gastric juice was measured. The patients with endoscopically diagnosed bile in the stomach (51 patients) had duodenogastric reflux significantly (P < 0.05) more often in the isotope examination than the patients without bile observed in the stomach (25 patients). The amount of bile as estimated endoscopically correlated well with the bile acid concentration of gastric juice. However, 18 patients with endoscopic bile reflux had no reflux in the isotope examination and 9 patients without endoscopic bile reflux had a mild reflux isotopically. The reflux estimations made endoscopically tend to give comparable results in general, but in many patients the results entirely differ from those obtained with the isotope method. This difference is mainly due to the invasive nature of the endoscopic examination.