Regulation of Recombinant Monoclonal Antibody Production in Chinese Hamster Ovary Cells: A Comparative Study of Gene Copy Number, mRNA Level, and Protein Expression
- 3 February 2006
- journal article
- research article
- Published by Wiley in Biotechnology Progress
- Vol. 22 (1) , 313-318
- https://doi.org/10.1021/bp0501524
Abstract
We performed a comparative analysis on CHO cells with varying recombinant monoclonal antibody production rates (qAb) and investigated the regulation of MAb production. Two families of CHO cells each ...Keywords
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