Effect of AGTH upon Artificially Induced Trichinosis in Rats with Special Reference to Eosinophilia

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Abstract
The marked eosinophilia due to an experimental Trichinella infection was greatly depressed but not abolished when ACTH was administered for short intervals. Effects of ACTH in animals with artificially induced trichinosis were exhibited by alterations of the inflammatory response to encysted larvae, alterations in the bone marrow, and the changes in the level of circulating eosinophils. Although modification of the host response to Trichinella infestation was obtained with ACTH there was no objective evidence that the infected rats benefited as a result of this treatment.

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