Effect of Bilirubin on Potassium Release from Cord Blood Erythrocytes
- 1 January 1980
- journal article
- research article
- Published by Japan Society for Cell Biology in Cell Structure and Function
- Vol. 5 (3) , 209-213
- https://doi.org/10.1247/csf.5.209
Abstract
To determine the developmental mechanism of neonatal jaundice and its prevention, the fragility of erythrocytes in umbilical cord blood and maternal blood was investigated by observing the release of K from them at a high concentration of bilirubin. The amount of K released from the erythrocytes increased in the presence of bilirubin and was more marked in erythrocytes from the umbilical cord than in those of maternal blood. An addition of cepharanthine to the erythrocyte suspension inhibited K release. Cepharanthine might be used as an antihemolytic drug against neonatal jaundice.This publication has 1 reference indexed in Scilit:
- Clustering and endocytosis of membrane receptors can be induced in mature erythrocytes of neonatal but not adult humans.Proceedings of the National Academy of Sciences, 1976