A Molecular Brake in the Kinase Hinge Region Regulates the Activity of Receptor Tyrosine Kinases

This publication has 50 references indexed in Scilit:

• Frequent activating FGFR2 mutations in endometrial carcinomas parallel germline mutations associated with craniosynostosis and skeletal dysplasia syndromes
  Oncogene, 2007
• PDGFRA Mutations in Gastrointestinal Stromal Tumors: Frequency, Spectrum and In Vitro Sensitivity to Imatinib
  Journal of Clinical Oncology, 2005
• Familial scaphocephaly syndrome caused by a novel mutation in the FGFR2 tyrosine kinase domain
  Journal of Medical Genetics, 2005
• The Active Conformation of the PAK1 Kinase Domain
  Structure, 2005
• Novel fibroblast growth factor receptor 3 (FGFR3) mutations in bladder cancer previously identified in non-lethal skeletal disorders
  European Journal of Human Genetics, 2002
• Distinct Missense Mutations of the FGFR3 Lys650 Codon Modulate Receptor Kinase Activation and the Severity of the Skeletal Dysplasia Phenotype
  American Journal of Human Genetics, 2000
• Structure of the Tie2 RTK Domain: Self-Inhibition by the Nucleotide Binding Loop, Activation Loop, and C-Terminal Tail
  Published by Elsevier ,2000
• Clinical spectrum of fibroblast growth factor receptor mutations
  Human Mutation, 1999
• A recurrent mutation in the tyrosine kinase domain of fibroblast growth factor receptor 3 causes hypochondroplasia
  Nature Genetics, 1995
• The CCP4 suite: programs for protein crystallography
  Acta Crystallographica Section D-Biological Crystallography, 1994