Fungal transformation of naphthalene
- 1 January 1978
- journal article
- research article
- Published by Springer Nature in Archiv für Mikrobiologie
- Vol. 117 (2) , 135-143
- https://doi.org/10.1007/bf00402301
Abstract
Eighty-six species of fungi belonging to sixty-four genera were examined for their ability to metabolize naphthalene. Analysis by thin-layer and high pressure liquid chromatography revealed that naphthalene metabolism occurred in forty-seven species belonging to thirty-four genera from the major fungal taxa. All organisms tested from the order Mucorales oxidized naphthalene with species of Cunninghamella, Syncephalastrum and Mucor showing the greatest activity. Significant metabolism was also observed with Neurospora crassa, Claviceps paspali and four species of Psilocybe. The predominant metabolite formed by most organisms was 1-naphthol. Other products identified were, 4-hydroxy-1-tetralone, trans-1,2-dihydroxy-1,2-dihydronaphthalene, 2-naphthol, 1,2-and 1,4-naphthoquinone.Keywords
This publication has 34 references indexed in Scilit:
- Patulin Biosynthesis: The Role of Mixed‐Function Oxidases in the Hydroxylation of m‐CresolEuropean Journal of Biochemistry, 1974
- Properties of a Yeast Cytochrome P‐450‐Containing Enzyme System which Catalyzes the Hydroxylation of Fatty Acids, Alkanes, and DrugsEuropean Journal of Biochemistry, 1973
- Arene oxides and the NIH shift: The metabolism, toxicity and carcinogenicity of aromatic compoundsCellular and Molecular Life Sciences, 1972
- Conversion of naphthalene to trans-naphthalene dihydrodiol: Evidence for the presence of a coupled aryl monooxygenase-epoxide hydrase system in hepatic microsomesBiochemical and Biophysical Research Communications, 1972
- The configuration of the 1,2-dihydroxy-1,2-dihydronaphthalene formed in the bacterial metabolism of naphthaleneBiochimica et Biophysica Acta (BBA) - General Subjects, 1971
- Fatty acid and hydrocarbon hydroxylation in yeast: Role of cytochrome P-450 in Candida tropicalisBiochemical and Biophysical Research Communications, 1971
- The Microbial Oxidation of Aromatic HydrocarbonsCRC Critical Reviews in Microbiology, 1971
- The NIH shift during the hydroxylation of aromatic substrates by fungiJournal of the Chemical Society D: Chemical Communications, 1971
- 1,2-Naphthalene oxide as an intermediate in the microsomal hydroxylation of naphthalene. VBiochemistry, 1970
- The role of arene oxide-oxepin systems in the metabolism of aromatic substrates. III. Formation of 1,2-naphthalene oxide from naphthalene by liver microsomesJournal of the American Chemical Society, 1968