HLA-B27, ARTHRITIS AND SPONDYLITIS IN AN ISOLATED COMUNITY IN PAPUA NEW GUINEA
- 1 April 1990
- journal article
- research article
- Published by Oxford University Press (OUP) in Rheumatology
- Vol. 29 (2) , 97-100
- https://doi.org/10.1093/rheumatology/29.2.97
Abstract
Rheumatic complaints in a sample of 109 individuals from an isolated community in Papua New Guinea were documented and 92/109 were tissue typed for HLA-B27. Eleven (10.1%) subjects had active peripheral arthritis, but 38 (34.9%) had previously suffered an episode of arthritis. In those with current peripheral arthritis, 6/10 (60%) were HLA-B27 positive compared to 15/58 (25.9%) with no history of arthritis (PP<0.05). Back pain was common. In 84/109 individuals the cause was mechanical injury; 24/72 (33.3 %) of these were HLA-B27 positive. Ankylosing spondylitis was identified in one HLA-B27-negative woman.Keywords
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