Food, reproduction and L'ongevity: Is the extended lifespan of calorie‐restricted animals an evolutionary adaptation?
- 1 April 1989
- Vol. 10 (4) , 125-127
- https://doi.org/10.1002/bies.950100408
Abstract
Calorie restriction results in an increased lifespan and reduced fecundity of rodents. In a natural environment the availability of food will vary greatly. It is suggested that Darwinian fitness will be increased if animals cease breeding during periods of food deprivation and invest saved resources in maintenance of the adult body, or soma. This would increase the probability of producing viable offspring during an extended lifespan. The diversion of limited energy resources from breeding to maintenance of the soma is seen as an evolutionary adaptation, fully compatible with the 'disposable soma' theory of the evolution of ageing.Keywords
This publication has 24 references indexed in Scilit:
- Ageing as a consequence of natural selectionPublished by Cambridge University Press (CUP) ,1986
- Lifetime breeding studies in fully fed and dietary restricted female CFY Sprague-Dawley rats. 1. Effect of age, housing conditions and diet on fecundityMechanisms of Ageing and Development, 1985
- Correlation between ultraviolet-induced DNA repair in primate lymphocytes and fibroblasts and species maximum achievable life spanMechanisms of Ageing and Development, 1984
- DNA Methylation Decreases in Aging But Not in Immortal CellsScience, 1983
- Some biochemical parameters of ageing in relation to dietary proteinMechanisms of Ageing and Development, 1983
- The relationship of DNA excision repair of ultraviolet-induced lesions to the maximum life span of mammalsMechanisms of Ageing and Development, 1981
- Serum profiles of LH, FSH, testosterone and 5α-DHT from 21 to 1000 days of age in AD Libitum fed and dietary restricted ratsExperimental Gerontology, 1981
- Survival and disease patterns in C57BL/6J mice subjected to undernutritionExperimental Gerontology, 1980
- Evolution of ageingNature, 1977
- Inverse correlation between species life span and capacity of cultured fibroblasts to bind 7,12-dimethylbenz(a)anthracene to DNAExperimental Cell Research, 1977