PURE RED-CELL APLASIA AND CHRONIC LYMPHOID LEUKEMIA - USEFULNESS OF FERROKINETIC MEASUREMENTS

  • 1 January 1981
    • journal article
    • research article
    • Vol. 23  (4) , 213-218
Abstract
Erythroblastopenia is probably not rare in chronic lymphocytic leukemia (CLL) but the diagnosis could be difficult. It produces a severe and rapidly developing anemia, without evidence of hemolysis. The chief differential diagnostic characteristic is the common bone marrow insufficiency of end-stage CLL. Fe kinetics measurements are typical, showing a total erythropoietic insufficiency, and a red cell utilization of radio-iron that is practically zero. Erythroblastopenia can be cured with corticosteroid treatment and sometimes with immunosuppressive treatment.