Delineation of nevus cell nests in inflammatory infiltrates by immunohistochemical staining for the presence of S100 protein

Abstract
Halo nevi (15) were stained for the presence of S100 protein by an unlabeled antibody peroxidase-antiperoxidase method. S100 protein was clearly identifiable within nevus cell nests in the inflammatory infiltrate. The presence of this substance helped to identify nevus cells in dense inflammatory infiltrates and confirm the histologic diagnosis of halo nevus.

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