ANGIOLYMPHOID HYPERPLASIA WITH EOSINOPHILIA OF THE SKIN - LIGHT MICROSCOPIC AND ULTRASTRUCTURAL-STUDY OF 4-CASES

  • 1 January 1981
    • journal article
    • research article
    • Vol. 89  (4) , 271-283
Abstract
A clinical, EM and light microscopic study of 4 patients with angiolymphoid hyperplasia with eosinophilia of the skin is presented. Light-microscopically the lesions were characterized by small size and superficial location, the proliferation of mostly delicate vessels with prominent endothelial hyperplasia and cellular areas without distinct vessel structures but with infiltrates of eosinophilic leukocytes, lymphocytes and plasma cells. Ultrastructurally a marked proliferation of endothelial cells and pericytes could be demonstrated, and the solid cellular areas were composed of solid vascular buds. A multi-layered basal lamina enclosed pericytes and external surfaces of endothelial cells. The differential diagnosis is discussed and it is emphasized that this lesion may be misinterpreted as angiosarcoma.