TISSUE COMPOSITION AND HALOTHANE SOLUBILITY IN THE HORSE

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Abstract
The halothane muscle/gas partition coefficients at 37°C for 26 samples of eight different muscles from four horses were found to depend significantly on the fat content of the muscle sample with a regression coefficient of 1.913 (SEM 0.109) per per cent ether-extractable fat content. The blood/gas partition coefficients in 24 horses showed a significant dependence on plasma triglyceride concentration (regression coefficient 0.00084 (SEM 0.00033) per mg dl−1), an insignificant positive dependence on plasma free and total cholesterol concentrations and, in multiple regression analysis, a negative dependence of borderline significance on packed cell volume (regression coefficient −0.01 (SEM 0.005) per per cent p.c.v.).

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