• 1 January 1981
    • journal article
    • research article
    • Vol. 33  (1) , 61-68
Abstract
A novel gas chromatographic procedure using a glass capillary column and electron-capture detection is described for the simultaneous assay in the brain of normetanephrine and 3-methoxytyramine, the 3-O-methylated metabolites of noradrenaline [norepinephrine] and dopamine, respectively. The procedure was used to quantitate these amines in whole rat brain and to demonstrate their postmortem accumulation.