The effect of ultraviolet light on some components of the nucleic acids. VI The origin of the U.V. sensitivity of deoxyribonucleic acid
- 1 January 1960
- journal article
- research article
- Published by Wiley in Recueil des Travaux Chimiques des Pays-Bas
- Vol. 79 (1) , 101-104
- https://doi.org/10.1002/recl.19600790111
Abstract
The rapid decrease in extinction of deoxyribonucleic acid in the first moments of irradiation with U.V. light (2537 Å) is due to the conversion of the pyrimidines into low‐absorbing substances. Thymine in this natural polymer reacts according to the so‐called “first irreversible reaction” shown by the free bases in solution. This could be demonstrated by means of a peculiar property of the irradiation product of thymine. Cytosine is supposed to react in the same way. The importance of this finding with respect to the lethal action of U.V. light on micro‐organisms is discussed.Keywords
This publication has 11 references indexed in Scilit:
- The effects of ultraviolet light on some components of the nucleic acids: III. Apurinic acidRecueil des Travaux Chimiques des Pays-Bas, 1959
- The effect of U.V.‐light on some components of the nucleic acids. IV. The influence of oxygen on the extent of the first irreversible reaction, shown by uracil and orotic acidRecueil des Travaux Chimiques des Pays-Bas, 1959
- The effect of U.V.‐light on some components of the nucleic acids. V. Reversibility of “the first irreversible reaction” under special conditionsRecueil des Travaux Chimiques des Pays-Bas, 1959
- Mating in the Reproduction of Bacterial VirusesPublished by Elsevier ,1958
- The effect of ultraviolet light on some components of the nucleic acids: II: In rapidly frozen solutionsRecueil des Travaux Chimiques des Pays-Bas, 1958
- The effect of U.V.‐light on some components of the nucleic acids: I. Uracil, thymineRecueil des Travaux Chimiques des Pays-Bas, 1958
- MONOCHROMATIC ULTRAVIOLET ACTION SPECTRA AND QUANTUM YIELDS FOR INACTIVATION OF T1 AND T2 ESCHERICHIA COLI BACTERIOPHAGESJournal of Bacteriology, 1954
- THE FORMATION OF APURINIC ACID FROM THE DESOXYRIBONUCLEIC ACID OF CALF THYMUSJournal of Biological Chemistry, 1952