The Proteins and RNAs Specified by Clo Mor Virus, a Scottish Nairovirus
- 1 November 1985
- journal article
- research article
- Published by Microbiology Society in Journal of General Virology
- Vol. 66 (11) , 2513-2516
- https://doi.org/10.1099/0022-1317-66-11-2513
Abstract
We have compared the structural polypeptides of an adult T-cell leukaemia (ATL) virus (ATLV) isolate from a Japanese patient with ATL with those of a similar virus derived from a Japanese macaque monkey. Both are distinct but related entities. Their core polypeptides p19 could not be distinguished, but p24, another core polypeptide, and their envelope glycopolypeptides differ. The human virus directs the synthesis of a single intracellular glycopolypeptide, gp68, while the macaque virus specifies two such glycopolypeptides, gp57 and gp50. Furthermore, the glycopolypeptides of both viruses are serologically distinct. Thus, these viruses represent subtypes of the ATLV family and the macaque virus is apparently not involved in human ATL.This publication has 1 reference indexed in Scilit:
- Synthesis of Bunyavirus-specific Proteins in a Continuous Cell Line (XTC-2) Derived from Xenopus laevisJournal of General Virology, 1985