REACTION OF MIXED CARBOXYLIC ANHYDRIDES WITH GRIGNARD REAGENTS. A CONVENIENT METHOD FOR THE PREPARATION OF 1,4- OR 1,6-DIKETONES

Abstract
It was found that mixed carboxylic anhydrides of γ- or ε-oxocarboxylic acids react with Grignard reagents to give 1,4- or 1,6-diketones in 32∼71% yields by one step procedure.