Nonosmolar Factors Affecting Renal Water Excretion

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Abstract
(Second of Two Parts)Physical and Emotional StressDuring their careful studies in conscious dogs, Verney and Rydin4 observed that exercise, as well as a sudden noxious stimulus capable of frightening the animal, was followed by a decrease in urine flow. Since then, the association of both physical31 and emotional103 stress with impaired water excretion has been well recognized. The original observations of Verney shed some light on the mechanism involved in this antidiuresis.104 He suggested that the associated changes in renal blood flow were not likely to account for the change in urine flow, and demonstrated that the antidiuresis . . .