A novel combination of prosthetic groups in a fungal laccase; PQQ and two copper atoms
- 2 July 1990
- journal article
- Published by Wiley in FEBS Letters
- Vol. 267 (1) , 6-8
- https://doi.org/10.1016/0014-5793(90)80273-l
Abstract
Extracellular laccase (benzenediol:oxygen oxidoreductase EC 1.10.3.2) from the lignin-degrading fungus, Phlebia radiata, was shown to contain a novel combination of electron carriers as its prosthetic groups. In addition to two copper atoms per enzyme molecule, one molecule of PQQ was included as a cofactor. The EPR spectrum exhibits features of type 1 and type 2 copper atoms. In the enzymatic reaction 4 molecules of lignin model compound, coniferyl alcohol, are oxidized per molecule of oxygen reduced to water. During the reaction coniferyl alcohol is transformed to dilignols.Keywords
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