COPPER AND IRON IN HUMAN BLOOD

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Abstract
In previous studies1 of the copper and the iron content of the blood of adults in normal and in various pathologic states we have noted the important interrelationship which exists between these two elements. Especially interesting is the hypercupremia that accompanies anemia. Using the iron content of the blood as a means of estimating the hemoglobin content, we have demonstrated that hypoferronemia is associated with hypercupremia. We have extended our investigation to the blood in infancy and childhood. The present study encompasses an attempt to establish the normal ranges of copper and iron which are necessary for the proper interpretation of the changes in the blood in this age period. METHODS The determinations of copper and iron were made during the months from September to December. Venous blood was drawn from the sagittal sinus of patients less than 1 year of age and from the cubital vein of older

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