β-Selective Epoxidation of Cholesterol Derivatives with Molecular Oxygen and Aldehyde Catalyzed by Manganese(II) Complex

Abstract
In the presence of a catalytic amount of bis(dipivaloylmethanato)manganese(II) (= Mn(dpm)2), various cholesterol derivatives are smoothly converted into the corresponding β-epoxides in good to high yields with combined use of molecular oxygen and isobutyraldehyde. These stereoselectivities are the reversal of the cases using peracid such as mCPBA.

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