Antibody-dependent and spontaneous lympholysis in urologic cancer patients
Open Access
- 1 June 1979
- journal article
- research article
- Published by Springer Nature in British Journal of Cancer
- Vol. 39 (6) , 667-675
- https://doi.org/10.1038/bjc.1979.118
Abstract
To evaluate cytotoxic function mediated by killer lymphocytes and macrophages in urological cancer patients, we examined antibody-dependent and spontaneous lympholysis of chicken erythrocyte target cells, which is mediated by macrophages. Our results demonstrate a discordance between cytotoxic mechanisms in cancer patients, killer-cell function being impaired whilst macrophage-mediated cytotoxicity was increased.Keywords
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