δ-Lactams: synthesis fromD-glucose, and preliminiary evaluation as a fucosidase inhibitor, ofL-fuconic-δ-lactam
- 1 January 1988
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 7,p. 483-485
- https://doi.org/10.1039/c39880000483
Abstract
Polyhydroxylated δ-lactams are a potential class of glycosidase inhibitors; the synthesis of L-fuconic-δ-lactam (7), which preliminary studies have shown to be a weak but specific α-L-fucosidase inhibitor, is described.Keywords
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