Synthesis of Flavonoids in Scutellaria spp. II. Synthesis of 2', 6'-Dioxygenated Flavones

Abstract
Five flavones dioxygenated at C-2'' and 6'' (5, 7, 2'', 6''-tetrahydroxy-, 5, 7, 2''-trihydroxy-6''-methoxy-, 5,2''-dihydroxy-7, 8, 6''-trimethoxy-, 5, 2'', 6''-trihydroxy-7, 8-dimethoxy-, and 5, 7, 2''-trihydroxy-8, 6''-dimethoxyflavone) isolated from Scutellaria spp. were synthesized to confirm their structures. Spectroscopic comparisons of the synthetics with the corresponding natural flavones confirmed the respective structures.

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