STIMULATION OF LONGITUDINAL BONE GROWTH BY HYPOPHYSEAL HORMONES IN THE HYPOPHYSECTOMIZED RAT

Publisher Website
Google Scholar
Abstract
The stimulating effect of different pituitary hormones on longitudinal bone growth was determined with tetracycline as an intravital marker in hypophysectomized rats. Growth hormone [GH] was the most effective growth stimulating pituitary hormone. At considerably higher doses, thyrotropic hormone (TSH) and prolactin also showed growth stimulating activity. TSH exerts its effect via the production of thyroxine, whereas the growth stimulation by prolactin seems to be a direct effect of this hormone, similar to the effect of GH. The LH [luteinizing hormone], FSH [follicle stimulating hormone], ACTH, MSH [melanotropin], vasopressin and oxytocin preparations did not stimulate longitudinal bone growth.

This publication has 0 references indexed in Scilit: