Association of Waist-Hip Ratio With Diabetes Mellitus: Strength and Possible Modifiers
- 1 July 1992
- journal article
- Published by American Diabetes Association in Diabetes Care
- Vol. 15 (7) , 912-914
- https://doi.org/10.2337/diacare.15.7.912
Abstract
Objectives To characterize the association between central obesity, as measured by the waist-hip ratio (WHR), and non-insulin-dependent diabetes mellitus (NIDDM), considering the effects of sex, age, overall obesity, and family history of diabetes. Research Design and Methods Case-control study nested within a community-based survey. We selected 151 subjects with NIDDM and 301 nondiabetic control subjects as a systematic sample of survey screening negative individuals. Results Odds ratios for NIDDM, comparing a high WHR (≥ 0.926 for men, ≥ 0.83 for women) to a low WHR were 4.72 with a 95% confidence interval of 2.39–9.34, and 2.17 with a 95% confidence interval of 1.03–4.58, for women and men, respectively, controlling for age, overall obesity, and a family history of diabetes. Women with high WHRs in the presence of these risk factors are notably at risk for diabetes. Conclusions Central obesity, as measured by the WHR, is importantly and independently associated with NIDDM.Keywords
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