Chromatin Structure of Epstein-Barr Virus
Open Access
- 1 September 1985
- journal article
- research article
- Published by Microbiology Society in Journal of General Virology
- Vol. 66 (9) , 1931-1940
- https://doi.org/10.1099/0022-1317-66-9-1931
Abstract
Summary The episomal copies of Epstein-Barr virus (EBV) DNA are in a chromatin structure in the lymphoblastoid cell line B95-8. Nucleosomes on EBV DNA have the same spacing as those in cellular chromatin. Some of the EBV DNA is not in nucleosomes; this probably corresponds to DNA which is being packaged. Several DNase hypersensitive sites have been mapped on the EBV genome and patterns of CpG methylation are examined.This publication has 17 references indexed in Scilit:
- Active viral genes in transformed cells lie close to the nuclear cage.The EMBO Journal, 1982
- A human‐human hybridoma system based on a fast‐growing mutant of the ARH‐77 plasma cell leukemia‐derived lineEuropean Journal of Immunology, 1982
- The ovalbumin gene is associated with the nuclear matrix of chicken oviduct cellsCell, 1982
- A 200 base pair region at the 5$prime; end of the chicken adult $beta;-globin gene is accessible to nuclease digestionCell, 1981
- Absence of nucleosomes in a fraction of SV40 chromatin between the origin of replication and the region coding for the late leader RNACell, 1980
- A stretch of “late” SV40 viral DNA about 400 bp long which includes the origin of replication is specifically exposed in SV40 minichromosomesCell, 1979
- Nucleosomal structure of Epstein-Barr virus DNA in transformed cell linesJournal of Virology, 1979
- An altered subunit configuration associated with the actively transcribed DNA of integrated adenovirus genesCell, 1977
- Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase IJournal of Molecular Biology, 1977
- Inhibition of Epstein-Barr virus DNA synthesis and late gene expression by phosphonoacetic acidJournal of Virology, 1976