Correcting the QT Interval for Heart Rate by a Simple Linear Regression Formula: Applicability in Clinical Practice

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Abstract
Several studies investigated the human heart rate (HR)-QT interval relationship using different formulae, but in clinical use the necessity of a simple means of correction is apparent. We assessed the resting supine HR-QT relation in health nonhospitalized subjects (age range 20-60 years, 494 men and 536 women) undergoing noninvasive diagnostic examination, and patients with a history or evidence of heart disease were excluded. The electrocardiographic data were recorded and calculated by a Marquette computer-assisted system (QT as mean of all standard leads). A linear relationship was found between the HR and QT interval in males and females, as follows: males (n = 494), QT - 524 ms, 2.05 HR, r = -0.85; females (n = 536), QT = 515 ms, 1.88 HR, r = -0.80. The correlation coefficients are highly significant in both cases (p

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