The Relationship of Carbohydrate Metabolism to Protein Metabolism

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Abstract
Adult male rats were first given a diet with the protein fed apart from the carbohydrate and then the same diet with most of the carbohydrate fed along with the protein. The immediate effect of this change in the time of feeding carbohydrate was a considerable improvement in N balance. After a few days, however, N balance returned to its original level. Subsequent separation of the times of ingestion of carbohydrate and protein caused a transient impairment of N balance. It has been concluded that protein utilization is affected by the presence of carbohydrate in the same meal. No change in N balance was observed in experiments involving similar alterations in the time of feeding fat. The giving of fat a short time before the protein meal was also without effect on N balance.