The most recent reports of relapsing febrile nodular nonsuppurative panniculitis indicate that up to now the disease has not been found to respond to any treatment. Miller and Kritzler,1in 1942, reported the first autopsy on a patient dying of this disease; they had given their patient sulfanilamide, sulfathiazole and sulfadiazine successively, with only transient benefit from sulfanilamide. They decided in retrospect that even this benefit was merely apparent and that the sulfonamide compounds were of no value. Sulfapyridine was apparently not tried. Christian's recent edition of Osler's testbook,2which shortens the name to "relapsing febrile nonsuppurative panniculitis,'' contains the statement that ``treatment should be symptomatic" and does not refer to any reported successful treatment or mention the use of sulfonamide compounds. Larkin, De Sanctis and Margulis,3in February 1944, reviewed the literature and reported the twentyeighth case of the disease