DIFFERENCES BETWEEN ANTERIOR PITUITARY SEX-STIMULATING HORMONES AND PREGNANCY-URINE SUBSTANCES AS TESTED IN THE MALE MAMMAL AND BIRD

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Abstract
Comparing gonadotropic anterior pituitary and pregnancy-urine extracts, distinct differences were found in their respective action on the genital system. First a so-called genokinetic ratio was defined it is obtained by dividing the relative change in weight of the accessories by that of testes as compared to the corresponding figures in the control littermates, which were taken as unity. This ratio was constantly twice as high in the pregnancy urine treated as in the pituitary treated animals, the averages being respectively 2.45 and 1.23 for the rats above 34 days and 1.26 and 0.58 for the rats under 34 days of age. In immature chicks and ducks, pituitary extracts induced precocious sperma-togenesis and accelerated comb-growth in the young chick, while pregnancy urine is entirely inactive on either testicular function.

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