CHANGES IN LABELING OF SOLUBLE AND INSOLUBLE RAT-BRAIN PROTEINS USING [TYROSINE-H-3 AS PRECURSOR DURING A LEARNING EXPERIMENT

  • 1 January 1975
    • journal article
    • research article
    • Vol. 34  (11-1) , 1863-1867
Abstract
The incorporation of intraventricularly injected L-[3H]-tyrosine into proteins from 3 rat brain regions was studied during the acquisition of a shock-motivated brightness discrimination. Separating the proteins by polyacrylamide gel electrophoresis revealed an increased labeling confined to only a few of the resolved slow-moving bands of soluble and insoluble hippocampus proteins. The labeling of visual cortex proteins showed only minute changes, while the auditory cortex proteins exhibited no differences between trained and nontrained animals.

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