Purulent Ocular Discharge in Neonates: Significance of Chlamydia trachomatis

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Abstract
Cultures for bacteria and chlamydiae were obtained from 100 infants with conjunctivitis that began during the first month of life. Sixty-nine infants were evaluated during well-child visits (group A); 31 were seen specifically for the ocular discharge (group B). Potentially pathogenic bacteria, predominantly Staphylococcus aureus, were cultured from 1/3 of the infants in each group. C. trachomatis was recovered from 3 infants (4%) in group A and from 10 (32%) in group B. Three infants with chlamydial conjunctivitis (2 in group A, 1 in group B) had only mild inflammation. Initial treatment with topical antibiotics was unsuccessful in eliminating the organism from seven of 11 infants.

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