Induction of the Mycelial Form of Candida albicans by Hydrolysates of Peptides from Seminal Plasma

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Abstract
Previous work led to the separation from seminal [bovine and human semen] plasma of a peptide fraction which promoted a high rate of germination of blastospores of C. albicans. An acid hydrolysate of this material is also highly active. A minimal amino acid mixture consisting of aspartic acid, lysine, histidine, threonine, proline and .beta.-alanine gave 90% germination in 4 h with 17 out of 28 strains examined. Glucose and inorganic phosphate were also required. Phosphate was not required for the activity of the original peptide fraction.
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