Acute Urticaria Associated with Streptococcal Infection

Abstract
Cases (81) of acute urticaria were treated over a 2 yr period. In 13 of 32 cases screened for streptococcal pharyngitis, positive throat culture and/or significant streptococcal exoenzyme antibodies (streptozyme test) were found. Other causative factors for the acute urticaria were excluded. .beta.-Hemolytic streptococcal infection may be a causative agent in many cases of acute urticaria and the infection may not always be clinically apparent. A throat culture and determination of streptococcal enzyme level are recommended as routine procedures in evaluating acute urticaria. Based on 1 case, discontinuing antibiotic therapy for a streptococcal infection when urticaria develops, even though necessary, might be inappropriate.

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