The monozygotic twin half-sib method for analysing maternal effects and sex-linkage in humans
- 1 April 1981
- journal article
- research article
- Published by Springer Nature in Heredity
- Vol. 46 (2) , 227-238
- https://doi.org/10.1038/hdy.1981.30
Abstract
The influence of maternal effects and sex-linked loci upon the statistics derived from an analysis of the families of monozygotic twins (the so called MZ half-sib design of Nance and Corey, 1976) is examined. If, as in the published analyses, the progeny sexes are considered jointly, maternal effects and sex-linkage may be confused. In the absence of sex-linkage a comparison of maternal and paternal half-sib covariances will often be a more powerful test for maternal effects than the conventional comparison of maternal and paternal parent-offspring covariances. If the progeny sexes are considered separately the analysis of sex-linkage presents no fundamental problems.Keywords
This publication has 9 references indexed in Scilit:
- Data from kinships of monozygotic twins indicate maternal effects on verbal intelligenceNature, 1980
- The power of the classical twin studyHeredity, 1978
- GENETIC MODELS FOR THE ANALYSIS OF DATA FROM THE FAMILIES OF IDENTICAL TWINSGenetics, 1976
- Genetic Studies of the Offspring of Identical Twins - A Model for the Analysis of Quantitative Inheritance in ManActa geneticae medicae et gemellologiae, 1976
- Insignificance of Evidence for Differences in Heritability of IQ between Races and Social ClassesNature, 1972
- Biometrical GeneticsPublished by Springer Nature ,1971
- Correlations between Relatives arising from Sex-linked GenesNature, 1963
- BIRTH WEIGHT IN COUSINSAnnals of Human Genetics, 1955