Understanding Substrate Specificity of Polyketide Synthase Modules by Generating Hybrid Multimodular Synthases
Open Access
- 1 October 2003
- journal article
- Published by Elsevier
- Vol. 278 (43) , 42020-42026
- https://doi.org/10.1074/jbc.m305339200
Abstract
No abstract availableKeywords
This publication has 31 references indexed in Scilit:
- Polyketide biosynthesis: a millennium reviewNatural Product Reports, 2001
- The biosynthetic gene cluster for the microtubule-stabilizing agents epothilones A and B from Sorangium cellulosum So ce90Chemistry & Biology, 2000
- Cloning and Heterologous Expression of the Epothilone Gene ClusterScience, 2000
- From molecular to modular cell biologyNature, 1999
- Knowledge-based design of bimodular and trimodular polyketide synthases based on domain and module swaps: a route to simple statin analoguesChemistry & Biology, 1999
- Tolerance and Specificity of Polyketide SynthasesAnnual Review of Biochemistry, 1999
- Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699Chemistry & Biology, 1998
- Cloning and sequence analysis of the putative rifamycin polyketide synthase gene cluster fromAmycolatopsis mediterraneiFEMS Microbiology Letters, 1998
- Modular Organization of Genes Required for Complex Polyketide BiosynthesisScience, 1991
- An unusually large multifunctional polypeptide in the erythromycin-producing polyketide synthase of Saccharopolyspora erythraeaNature, 1990