Response of the Syrian Hamster to the Virus of Newcastle Disease
- 1 June 1948
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 68 (2) , 293-294
- https://doi.org/10.3181/00379727-68-16460
Abstract
A California strain of Newcastle Virus #11914 was carried intracerebrally through 200 passages in Syrian hamsters. The incubation period decreased gradually from 2 to 6 days, in the early passages, to approx. 12 hrs. after the 190th passage. Despite the apparent increased infectivity with progressive passages the hamster-adapted Newcastle virus of the 200th titered only slightly higher in 4-weeks-old hamsters than that of the 49th or 92d passages. After the 92d passage, the hamster-adapted virus was non-pathogenic for chickens when inoculated intramusc. or subcut.Keywords
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