1. A preliminary report is submitted on the aspiration biopsy of the prostatic gland. 2. A technique of prostatic biopsy is described, being relatively free of complications and readily accepted by patients as an office procedure for routine screening for carcinoma of the prostate. 3. A modification of the Giemsa staining technique is performed so as to evidence pathognomic elements within the interior of the nucleus, specifically in the altered nucleolus.