Solid Phase Acylation of Phosphonoacetates Synthesis of β-Keto Phosphonates from Polymer Bound Phosphonoacetate
- 1 April 1999
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 29 (8) , 1271-1275
- https://doi.org/10.1080/00397919908086102
Abstract
Solid phase synthesis of phase synthesis of β-keto phosphonates, via acylation reaction of polymer bound phosphoacetate with carboxylic acid chlorides in the presence of magnesium chloride-triethylamine followed by cleavage of resin with concomitant decarboxylation, is described.Keywords
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