A Possible Step in the Origin of the Genetic Code
- 1 January 1972
- journal article
- research article
- Published by Wiley in Israel Journal of Chemistry
- Vol. 10 (2) , 287-292
- https://doi.org/10.1002/ijch.197200034
Abstract
It is suggested that the earliest coding polynucleotides contained a high proportion of alternating sequences of purines and pyrimidines, and that these sequences coded for polypeptides in which hydrophobic and hydrophylic amino acids alternated. Structural properties of such alternating polypeptides are discussed.Keywords
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- Sequence and structure homologies in bacterial and mammalian-type cytochromesJournal of Molecular Biology, 1971
- The origin of the genetic codeJournal of Molecular Biology, 1968