In Vitro Activities of Ketolides HRM 3647 and HRM 3004, Levofloxacin, and Other Quinolones and Macrolides against Neisseria spp. and Moraxella catarrhalis

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Abstract
In vitro activities of the ketolides HRM 3647 and HRM 3004 against pathogenic Neisseria gonorrhoeae and N. meningitidis , saprophytic Neisseria isolates, and Moraxella catarrhalis were determined. The comparison of ketolide activities with those of the other macrolides shows a much better activity in the majority of species, with macrolide MICs at which 90% of the isolates are inhibited between 8- and 10-fold higher.