SYNTHESIS AND BIOLOGICAL ACTIVITY OF BRANCHED CHAIN-SUGAR NUCLEOSIDES1

Abstract
2′-Alkyl derivatives of cytidine and thymidine have been synthesized. 2′-Deoxy-6,2′-methanocytidine has also been prepared. Among them, 2′-deoxy-2′-methylidene-cytidine exhibited potent antitumor activities.

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