Biological properties of Cis- and Trans- dichlorodiammineplatinum
- 1 July 1980
- journal article
- research article
- Published by Wiley in Cell Biology International Reports
- Vol. 4 (7) , 697-700
- https://doi.org/10.1016/0309-1651(80)90210-6
Abstract
Cis- and Trans- dichlorodiammineplatinum (II) inhibit the development of the sea urchin eggs. The inhibition is prevented by N-acetylcysteine, glutathione and alpha-mercaptopropionylglycine. Sulfhydril groups appear as a cellular target for these platinum compounds.Keywords
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