Stereocontrolled total synthesis of galactostatin from serine
- 1 January 1991
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 21,p. 1576-1578
- https://doi.org/10.1039/c39910001576
Abstract
An efficient stereoselective total synthesis of (–)-galactostatin (–)-1 from N-tert-butoxycarbonyi-2,3-isopropylidene L-serine methyl ester (21% overall yield) is described via thiazole intermediates serving as protected aldehydes; the parallel synthesis of the natural antipole (+)-1 starts from D-serine.Keywords
This publication has 0 references indexed in Scilit: