Frequency of Celiac Disease in Individuals with Down Syndrome in the United States
- 1 May 2001
- journal article
- research article
- Published by SAGE Publications in Clinical Pediatrics
- Vol. 40 (5) , 249-252
- https://doi.org/10.1177/000992280104000502
Abstract
Ninety-three individuals with Down syndrome (DS) were screened to investigate the prevalence of celiac disease (CD) in the United States. Five of the 93 individuals were antiendomysial antibody (EMA) positive. Of the 5 who tested positive for EMA, 4 were biopsied, 1 refused biopsy. Three of the 4 individuals biopsied manifested changes of CD on small bowel biopsy. This gives a frequency of 3.2% of confirmed CD in our DS individuals and suggests the need for periodic screening for celiac disease in this population.Keywords
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