Resistance Relationships in Mycobacterium smegmatis ATCC 607 to Phages Sensitive or Resistant to both Chloroform and Streptomycin Sulphate

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Abstract
Four of 8 mycobacteriophages did not form plaques after they were exposed to chloroform. Phages sensitive to chloroform did not produce plaques when plated on media containing 1000 .mu.g/ml of streptomycin sulfate. The same concentration of dihydrostreptomycin sulfate did not interfere with plaque formation. Mutants of M. smegmatis resistant to each of the 8 phages were isolated. Sensitivity or resistance to chloroform and streptomycin sulfate and phage resistant bacterial mutants may provide a basis for classifying the mycobacteriophages.

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