Effect of Gholic Acid Administration on Taurine Concentration of Rat Organs.

Publisher Website
Google Scholar
Abstract
Taurine concentration of liver, heart, kidney, spleen and skeletal muscle of the rat was measured after feeding cholic acid. No changes in taurine concentration could be found as a result of cholic acid administration. There was no effect even when the diet was low in sulfur amino acids. It is inferred that exogenous taurine is not used to a great extent for the formation of taurochblic acid. Arrest of growth and symptoms of cysteine deficiency in rats fed cholic acid are correlated with loss of endogenous taurine. As the latter compound seems to be formed at all times, the supply of sulfur amino acids is lowered thus creating deficiency symptoms.

This publication has 1 reference indexed in Scilit: